- What is Poison Ivy: signs and symptoms
- Poison Ivy treatment with Prednisolone (Prednisone)
- Prednisolone (Prednisone) Dosage
- Prednisolone (Prednisone) during pregnancy
- Is Prednisone (Prednisolone) a corticosteroid?
- Prednisone (Prednisolone) for allergies. Dosage
- Prednisone (Prednisolone) for bee sting
Ivy poison refers to plants, touching the leaves of which you can burn yourself or get other effects - for example, in the form of general poisoning. It has everything poisonous - the stem, the leaves, the flowers, and the fruits. Most people have a severe allergic reaction to this plant. Discover how Prednisolone (Prednisone) can help you to get rid of the serious allergic reaction effectively.
Prednisone is a drug from the group of adrenal cortex hormones (glucocorticosteroids). It contains the substance Prednisolone.
What is Poison Ivy: signs and symptoms
Allergy to this plant is observed in 70% of people. It manifests itself as follows: a short time after contact with poison ivy, a person has itchy swelling with redness, blisters and swelling of the skin. There is a rash that can spread all over the body and sometimes does not go away for a long time. Contact with the poisonous plants can occur directly - if a person touches it, or can be indirect - if you touch clothing, tools or animals, which have the irritating ivy oil.
Factors that increase the likelihood of allergic contact dermatitis:
- Work or rest in the locality where these plants grow during spring, summer and autumn;
- Contacts with pets or animals that had contact with the plant;
- Contact with clothing or objects that have come into contact with these plants;
- The effect of smoke from these plants, when they burn.
The main symptoms of the rash are:
- Itching of the skin at the place of contact with the plant;
- Red streaks or redness in the area of contact;
- Small blisters or swelling (urticaria);
- Blisters containing fluid.
The rash, as a rule, manifests itself 8-48 hours after contact with the plant. But it can appear in 5 hours or 15 days. Usually, if the allergy is manifested for the first time, the rash appears within a week. It appears in new places for several days, but only where there was contact with the plant.
The rash is not contagious. It cannot be transmitted after its manifestation, even with contact with blisters, as the oils have already absorbed or washed off the skin. It may seem that the rash is spreading, but this can occur with early contact or in a contact with objects that may contain oils. The more oil gets on the skin, the sharper the skin reaction. Acute reactions that occur in a small amount of oil may be in people who are very sensitive to this allergen.
Serious symptoms may include:
- Swelling of the face, mouth, neck, genitals and eyelids.
- A large number of blisters, from which the liquid is secreted.
If the poison ivi treatment is not available, the rash lasts from 10 days to three weeks. But in people who are very sensitive to oil, the rash can last for six weeks.
Poison Ivy treatment with Prednisolone (Prednisone)
Prednisone is a synthetic hormone, which has a pronounced anti-inflammatory and anti-allergic effect. Despite the effectiveness, Prednisolone (Prednisone) is used in allergies and Poison Ivy treatment only in emergency cases. The drug is effective in the development of anaphylactic shock, as it activates the production of adrenaline in the body.
In addition, prednisolone inhibits the accumulation of immune bodies in the affected area of the body, suppressing phagocytosis and aggression of cell enzymes. This property of the drug helps to reduce the intensity of the inflammatory process.
Poison ivy phytodermatitis treatment with Prednisolone (Prednisone)
For severe dermatitis caused by contact with poison ivy, the drug Prednisone or Prednisolone is used. The treatment regimen with a single use of Prednisone is presented in the table below.
An alternative treatment regimen for severe advanced inflammation is the administration of Prednisolone (Prednisone) at a dose of 20 mg 2 times a day for at least 7 days. It is usually not necessary to gradually reduce the dose after this short course.
If it is difficult for patients to comply with the prescribed treatment for poison ivy, triamcinolone acetonide can be administered intramuscularly (Kenalog-40, Aristocort 40 mg, suspension). Commercially available “portioned” forms of a corticosteroid (for example, Medrol Dosepak) are not recommended because they contain an amount of the drug that is insufficient to cure poison ivy.
As a rule, their use leads to a recurrence of rash and itching after partial improvement in the first days of treatment (the effect of withdrawal). The condition of patients who are not required to undergo a corticosteroid during the initial examination may significantly worsen in 1-2 days after a visit to the doctor. Such patients should be advised to take Prednisone if their condition worsens.
Table: Prednisolone (Prednisone) in case of severe dermatitis after contact with poison ivy (for adults).
|Day||Dosage (mg / day). 10mg tablets are taken 1 time a day in the morning.|
Prednisolone (Prednisone) Dosage
The dose of the drug Prednisolone (Prednisone) depends on the individual characteristics of the body and the course of the disease, as well as the appointment of a doctor. Prednisolone tablet should be washed down with a glass of water, without chewing. The recommended dose of Prednisolone for adults is 20-30 mg per day with a gradual decrease to 5-10 mg of the drug. The initial dose of Prednisolone for children is not more than 2 mg (based on 1 kilogram of the child's weight) during the day, previously divided into 4-6 receptions.
The maintenance therapeutic Prednisolone dosage is 300 to 600 μg per kg. during the day. The termination of therapeutic treatment should be carried out gradually, reducing dosage. Numerous patient reviews are mostly positive. Patients note that in the most severe cases prednisone effectively and quickly removes allergy symptoms, acute diseases of various etiologies. It perfectly removes allergic itching and swelling.
Prednisolone (Prednisone) and Pregnancy
Prednisolone should be used during pregnancy only when prescribed by a physician who compares the risks of using the drug with the possible effects that the drug may have on the development of the fetus.
The indications for Prednisolone (Prednisone) during pregnancy may be as follows:
1. High risk of miscarriage in the 2nd trimester and preterm birth in the 3rd trimester. Admission of glucocorticoids in this case causes the maturation of surfactant - a substance that provides the function of respiration of the fetus;
2. With a rare pathology in women - hyperandrogenism. During this condition, the adrenal glands and ovaries of the woman produce an increased amount of androgens - male sex hormones. In this case, the uterus tone increases, resulting in an increased risk of miscarriage.
If the fetus is male, the imbalance increases - the hormonal system begins to work in the future baby from the moment of formation of its reproductive system - from the beginning of the 2nd trimester. Prednisolone" blocks the production of androgens. This condition is controlled by a special prednisolone test - during pregnancy, the level of androgens is determined by applying a drop of urine to the test strip;
3. If a woman has a history of diseases - for example, systemic lupus erythematosus - or asthma, hepatitis, antiphospholipid syndrome. The body can respond to pregnancy with an autoimmune response. As a result, the fetus will be perceived as a foreign body, and antibodies will be produced to it, which contribute to its rejection.
When it is vital, the use of Prednisolone (Prednisone) has only one contraindication - individual intolerance. It is quite rare. A single use of the drug Prednisone rarely has undesirable side effects.
Proper administration and calculation of the dosage of Prednisolone individually reduce the occurrence of side effects, however, it is extremely dangerous to take Prednisone yourself, especially for a long period.
During pregnancy, Prednisolone helps to carry the fetus and go to natural childbirth in women with a history of autoimmune diseases, rheumatism, polyvalent allergies, and many other organic and systemic diseases.
However, prolonged use of the drug Prednisolone (Prednisone) is considered undesirable - it adversely affects the formation of the fetus. It was noted that the risk of underdevelopment of the urinary system, the appearance of a cleft lip and cleft palate, dysfunction of the adrenal cortex, and fetal growth retardation increase.
With the introduction of low doses of the drug Prednisolone, no negative effects from its admission in the formation of the organic systems of the fetus and the lag in the psychophysical development of an already born baby were observed.
Dosage forms of the drug Prednisolone (Prednisone) and its use during pregnancy
Prednisolone (Prednisone) can be prescribed to pregnant women in any form, depending on the appropriateness and diagnosis.
Prednisolone (Prednisone) is available in the form of tablets with a dosage of 5, 10, 20 and 40 mg. There is also a form of injection - ampoules with a solution of 30 and 25 mg for intravenous and intramuscular administration, eye drops and 0.5% ointment for local use.
If the course of treatment is long, pills are used - the dosage is adjusted individually. Taking the drug Prednisolone (Prednisone) is required at certain times during the meal, without shifting the time for more than 30 minutes - this is extremely important.
In case of force majeure situations and a single use of the drug, the dose is injected.
Is Prednisone (Prednisolone) a corticosteroid?
Prednisone (Prednisolone) is a synthetic corticosteroid.
Corticosteroids are a subclass of steroid hormone drugs. In a healthy body, these hormones are produced by the adrenal glands. Each patient receiving hormonal therapy is recommended to get acquainted in detail what corticosteroids are, what drugs they are presented with, how they differ and how they act on the body. Especially carefully read the sections on contraindications and side effects.
Natural corticosteroids are the hormones of the adrenal cortex, which are divided into glucocorticoids and mineralocorticoids.
The first are cortisone and hydrocortisone. These are steroids with anti-inflammatory action, puberty, stress response, kidney function, and pregnancy are under their control. They are inactivated in the liver, excreted in the urine.
Mineralocorticosteroids include aldosterone, which retains sodium ions, increases the excretion of potassium ions from the body.
In medicine, synthetic corticosteroids are used, which have the same properties as natural ones. They temporarily suppress the inflammatory process.
Synthetic corticosteroids lead to tension, stress, can reduce immunity, block the process of regeneration. Long-term use of corticosteroids is impossible.
From the drawbacks of these drugs can be identified suppression of the function of natural hormones, which can lead to disruption of the adrenal glands.
Relatively safe synthetic corticosteroids are Prednisone (Prednisolone), Triamcinolone, Dexamethasone, and Synalar (fluocinolone), which are highly active but have fewer side effects.
Prednisone (Prednisolone) for allergies. Dosage
Prednisolone is a potent hormonal agent that has immunomodulatory, anti-inflammatory and anti-histamine therapeutic effects. In addition, it can increase the effect of the use of other drugs of this therapeutic group.
The use of Prednisolone for the treatment of allergies in children or adults is made by the decision of a specialist individually. The doctor takes into account the indications and neglect of the disease. According to patient reviews, for the treatment of allergies, tablets and injections of a similar drug are used predominantly.
The drug Prednisone (Prednisolone) eliminates the symptoms of allergies, increases the number of platelets and red blood cells in the bloodstream, which helps the patient recover in the shortest possible time.
Prednisolone is effective in the presence of an acute allergic reaction: angioedema, itchy skin, asthma. It helps to suppress the production of histamine, helps activate a large amount of adrenaline. Prednisolone constricts blood vessels, increases blood pressure, eliminates puffiness.
Indications for the drug Prednisone (Prednisolone) for allergies
Prednisolone injection is used as an emergency measure of assistance in the presence of anaphylactic shock, exacerbations of food allergic reactions. Prednisolone is administered intravenously or intramuscularly every 5 hours for 3-5 days. Prednisolone can be prescribed during Quincke's edema in a single dose.
The indications for the use of prednisolone tablet form for allergies to children and adults are difficult pathological processes of a chronic nature, such as asthma or urticaria.
During asthma, hormonal treatment is carried out for 3-4 weeks or months. Longer use of prednisolone can cause addiction to the intake of corticosteroids from the outside. The organism will cease to produce them on its own.
Dosage of Prednisone (Prednisone) tablets
After a long parenteral therapy, adhering to the principle of the gradual cancellation of steroid drugs, doctors can transfer the patient to oral treatment (use of pills). Dosages of Prednisolone for allergies are selected by a specialist individually, taking into account age indicators and symptoms of the disease. The general scheme of use of the drug lasts about 10-15 days.
Pills of Prednisolone for allergies are taken orally, without chewing:
- Adults: 20-30 mg / day, with a transition to 5-10 mg;
- Children: 1-2 mg / kg / day (for 5 doses).
In the process of applying Prednisolone tablets, the following prescriptions should be observed:
- Prednisolone is swallowed whole, the tablets are not crammed and washed down with a small amount of water.
- Prednisolone tablets are taken directly in the morning. This is due to the fact that the adrenal hormones are naturally produced from 6 to 8 in the morning. Therefore, it is recommended to take the medicine during this period. When the daily dose is too large, it is divided into 2-3 doses.
- Discontinuation of Prednisolone is carried out for 3-5 days.
Prednisone (Prednisolone) for bee sting
First aid in the apiary with bee stings from hives
Anaphylactic shock is an allergic reaction of the body to the effects of various pathogens: food, plant pollen, bee venom and wasps, etc.
In case of anaphylactic shock, there should be a first-aid kit with the following drugs in the apiary: ampoules of Calcium Chloride or Gluconate, Adrenaline, Cordiamine, Caffeine, Prednisolone, Aminophylline.
When a bee bite a person develops swelling of the bite site and the surrounding parts of the body: hands, feet, eyelids. Swelling of the nasopharynx is especially dangerous - a person can suffocate.
The apiary with bee hives is usually located in the forest, far from the hospital. Therefore, apiary workers need to be able to provide first aid at the first signs of the development of anaphylactic shock on bee sting.
The following measures should be taken so that the victim does not die before the arrival of the doctors:
- Remove the sting. At the same time you need to call an ambulance. Before the arrival of the doctors you should perform all the necessary manipulations.
- In a mild condition after being bitten by a bee, it is necessary to drink an antihistamine pill.
- In a serious condition of the victim, you need to lay him in a horizontal position, turning his head on his side to avoid asphyxiation by vomiting masses or by dropping the tongue.
- Fix the lower jaw so that the tongue does not sink.
- Bottom limbs (feet) need to be warmed with bottles or a hot water bottle.
Professional actions should also be performed: use a sterile single-use syringe to crush the bite site (after removing the sting) with adrenaline - to make an adrenalin blockade in order to stop the movement of the allergen in the body. Adrenaline is injected subcutaneously with no more than 1 ml in fractional doses. After the introduction of the drug, it is necessary to cover the bite with a cold bandage or a bubble with ice.
It is necessary to introduce the following drugs by injection:
1. Cordiamin, caffeine - to support cardiac activity.
2. Prednisolone (Prednisone) is administered intravenously or intramuscularly - to relieve puffiness. The dose of Prednisolone for an adult is 60 mg, for children up to 10 years old - 30mg (1 ampoule), older than 10 years - 60mg.
3. A calcium preparation is injected into a vein - calcium chloride or gluconate. Cordiamine and adrenaline can be administered every 15 minutes, taking into account blood pressure control - until the pressure rises.
4. Now it is possible to inject intramuscularly solution Tavegil or Suprastin: for children under 5 years old - 1 ml each, from 5 to 10 years old - 2 ml, over 10 years old and adults - 4 ml of the drug.
5. To improve respiratory function, intravenous injection of aminophylline is recommended.
In case of pronounced swelling of the larynx and swelling of the tongue, a tracheotomy is necessary - a tube is inserted into the respiratory throat through an incision in the neck. Performing this procedure requires professional skills.
Without going deep into medical subtleties, you should know that with the development of anaphylactic shock in humans, deep disturbances in the work of the kidneys, cardiac, pulmonary, nervous and all other body systems can occur.
Therefore, follow all the rules of being in the apiary near the beehives - for your guests must be issued special suits in which the hands and faces are protected.
You must acquaint guests with the rules of conduct in the apiary, warning of the possible danger of being bitten by bees from hives. At the apiary should be properly equipped first aid kit.